Primary Human Bladder Smooth Muscle Cells

Primary Bladder SMC cultured directly from their source organ tissue, not modified. Variety of donors without accumulated mutations of immortal cell lines.
  Lifeline® Normal Human Primary Bladder Smooth Muscle Cells (HBSMC), when grown in VascuLife® SMC Smooth Muscle Cell Culture Medium, provide an ideal low serum (5%) culture model for the study of angiogenesis, atherosclerosis, diabetes or vascular/pulmonary biology. Primary Bladder Cells for the Best Research Outcomes Primary Bladder Smooth Muscle Cells are cryopreserved after primary culture to ensure the highest viability, purity and plating efficiency. Primary Bladder Cells have been directly cultured from their source organ tissue and haven't been modified in any way for true research results. Primary Bladder Smooth Muscle Cells come from a variety of donors without the accumulated mutations found in immortal cell lines. The cells are isolated from tissue, plated onto culture vessels, expanded, harvested and cryopreserved.  Our Human Smooth Muscle Cells are quality tested in VascuLife SMC Medium and demonstrate optimal low serum growth over a period of at least 15 population doublings at rates equal to or greater than other serum-supplemented media. Primary Bladder Smooth Muscle Cells are not exposed to antimicrobials or phenol red when cultured in VascuLife SMC Medium, an advantage since these supplements can negatively impact experimental results. Lifeline offers these traditional supplements; however, they are not needed, or recommended, to achieve optimal cell performance in most research applications. 500,000 cells per vial

(IM-HBlSMC) provided by Innoprot have been developed by immortalizing primary human bladder smooth muscle cells with SV40 Large T antigen.,

Immortalized Human Bladder Smooth Muscle Cells

Primary Human Bladder Smooth Muscle Cells

Induction and modulation of smooth muscle differentiation in Xenopus embryonic cells - Barillot - 2008 - Developmental Dynamics - Wiley Online Library

Urinary bladder: Anatomy, function and clinical notes

Characterizing relaxin receptor expression and exploring relaxin's effect on tissue remodeling/fibrosis in the human bladder, BMC Urology

Smooth Muscle – Anatomy & Physiology

Apigenin inhibits cell migration through MAPK pathways in human bladder smooth muscle cells

Smooth Muscle-Like Cells Generated from Human Mesenchymal Stromal Cells Display Marker Gene Expression and Electrophysiological Competence Comparable to Bladder Smooth Muscle Cells

Integration of proteomic and transcriptomic profiles identifies a novel PDGF-MYC network in human smooth muscle cells, Cell Communication and Signaling