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Frontiers Multiparameter Optimization of Trypanocidal Cruzain Inhibitors With In Vivo Activity and Favorable Pharmacokinetics
PDF) Use of a novel rapid and resource-efficient cassette dosing approach to determine the pharmacokinetics and CNS distribution of small molecule 7-transmembrane receptor allosteric modulators in rat
Scatter plots showing the predictions for clearance after IV dosing
Plasma clearance (CLp) values for ten additional compounds from
Chromatin-Associated Molecular Patterns (CAMPs) in sepsis
Toxics, Free Full-Text
Preclinical Pharmacokinetics and In Vitro Properties of GS-441524, A Potential Oral Drug Candidate for COVID-19 Treatment
Prediction of in vivo CL int,u in hepatocytes (A and C) and microsomes
Recombinant Human TNF-alpha Protein (210-TA)
Building a better NET: Neutrophil extracellular trap targeted therapeutics in the treatment of infectious and inflammatory disorders - Research and Practice in Thrombosis and Haemostasis
a) Evidence in support of a link between blood-brain barrier failure
Prediction error for linearly scaled CLp values for hypothetical drugs
Mechanistic insights on clearance and inhibition discordance between liver microsomes and hepatocytes when clearance in liver microsomes is higher than in hepatocytes - ScienceDirect
Plasma clearance and tissue uptake of radiolabeled LPS and HDL-LPS. LPS